The focus of my research is on the development and application of statistical and computational methodologies for functional genomics data such as gene expression (microarray and RNA-seq), chIP-Seq and proteomics. Applications of this work have included such complex traits as diabetes, cancer and alcoholism. There is also a strong interest in our group in network inference, particulalry for applications in infectious disease. Related to these analyses is a long standing interest in data cleaning and integration.

BioPAX consortium (2010) BioPAX - A community standard for Pathway Data Sharing. Nature Biotechnology. In Press

Grey F, Tirabassi R, Meyers H, Wu G, McWeeney S, Hook L, Nelson JA.(2010) A viral microRNA down-regulates multiple cell cycle genes through mRNA 5'UTRs. PLoS Pathogens. 2010 Jun 24;6(6):e1000967. PMID: 20585629

Bottomly D, Kyler S, McWeeney S, Yochum G (2010) Identification of Β-Catenin binding regions in colon cancer cells using ChIP-Seq. Nucleic Acids Research. Nucleic Acids Res. 2010 May 11. [Epub ahead of print] PMID: 20460455